The Nanoscale Spectroscopy and Photoinduced Phenomena Lab
Congratulations
Arunavo Chatterjee received RSC Adv. Prize for Best Oral Presentation in the 4th International Conference on Emerging Smart Materials in Applied Chemistry (ESMAC-2023) & Interdisciplinary Science for Sustainability as a part of the Diamond Jubilee Celebration of Indian Photobiology Society (IPS) held at KIIT Bhubaneswar in November 2023.
Works of Pradip Pattanayak et al. recently got accepted for publication in Chem. Mater. and Adv. Opt. Mater. (see the Publications tab)
Research Highlights:
Photophysical characterization of new organic and inorganic molecules in microheterogeneous environments
We synthesize new biologically compatible organic and inorganic fluorophores, characterize them and apply in host-guest chemistry. Knowledge on binding of compounds to bio-compatible carriers and their subsequent transit followed by release to the target sites need to be known essentially to develop drug delivery.
Host-guest interaction and applications in biological environments
The bound guest molecules to corresponding hosts may change the morphology of the latter subsequently generating molecular suprastructures that create provisions for trapping ions. The dynamics of the process is understood using various spectroscopic techniques.
Synthesis and application of metal nanoparticles and nanoclusters in drug delivery
We synthesize noble metal nanoparticles and nanoclusters and apply them in drug delivery following biological compatibility. The metal nanoclusters show fluorescence signals as opposed to the nanoparticles that makes them usable as bio-markers. Guest-host chemistry can be applied to develop bio-remedies for various physiological malfunctions.
Carbon nanoparticles in photoinduced energy/electron transfer
Photoinduced electron transfer is a smart concept to learn as this encompasses various applications including energy harvesting devices. We use carbon based nanomaterials, including nanoparticles, nanotubes and nanoplatelets to look into interactions with various energy donating/accepting substances in view of understanding the underlying dynamics.
Development of crystalline polymorphs for photophysical tuning
New organic compounds are synthesized in this venture through structural engineering and crystals are produced intuitively so that the materials can be used various applications including light guides, OLEDs, room temperature phosphorescent substances, etc.
Fluorescence Lifetime Imaging (FLIM) and Fluorescence Correlation Spectroscopy (FCS)
These microscopy based techniques are used in our laboratory to justify the positioning of various guests in bio-compatible hosts, such as, lipid vesicles. Entrapment of the fluorescent species withing bilayers alters the inherent photophysics of the guests that are significant to understand before applications to drug delivery.
Selected Recent Publications:
M. Mukherjee, A. Chatterjee, S. Bhunia and P. Purkayastha, Hydrophobic Chain-Induced Conversion of Three-Dimensional Perovskite Nanocrystals to Gold Nanocluster-Grafted Two-Dimensional Platelets for Photoinduced Electron Transfer Substrate Formulation, J. Phys. Chem. Lett. 2023, 14, 8251-8260.
P. Pattanayak, A. Nandi, S. K. Seth and P. Purkayastha, Heavy-Element-Free Triplet Accessibility in Pyrene-Core Compounds at Room Temperature by Microcrystal Engineering, J. Mater. Chem. C 2023, 11, 11252-11261.
R. Sinha, O. S. Jaykishan and P. Purkayastha, A curated graphene quantum dot-tetrakis(m-nitrophenyl)porphyrin-based photosensitizer for effective singlet oxygen generation through energy transfer, Langmuir 2023, 39, 11108-11118.
I. Mukherjee, H. Dekate and P. Purkayastha, On the Effect of Folic Acid Derived Carbon Nanodots in Modulating the Noncanonical I-Motif DNA Structures, ACS Appl. Nano Mater. 2023, 6, 6380-6387.
A. Chatterjee, A. K. Sharma, S. Pramanick, O. S. Jaykishan and P. Purkayastha, Dual stimuli responsive BSA-coated silver nanocluster-driven “FRET on-off” within niosomal membrane: detailed design and mechanism, J. Phys. Chem. C, 127, 2023, 797-806.
A. Chatterjee, Ruturaj, M. P. Chakraborty, S. Nandi and P. Purkayastha, Biocompatible and optically stable hydrophobic fluorescent carbon dots for isolation and imaging of lipid rafts in model membrane, Anal. Bioanal. Chem., 414, 2022, 6055-6067.
A. Chatterjee, A. Sharma and P. Purkayastha, Development of a carbon dot and methylene blue NIR-emitting FLIM-FRET pair in niosomes for controlled ROS generation, Nanoscale, 14, 2022, 6570-6584.