We synthesize new biologically compatible organic and inorganic fluorophores, characterize them and apply in host-guest chemistry. Knowledge on binding of compounds to bio-compatible carriers and their subsequent transit followed by release to the target sites need to be known essentially to develop drug delivery.
The bound guest molecules to corresponding hosts may change the morphology of the latter subsequently generating molecular suprastructures that create provisions for trapping ions. The dynamics of the process is understood using various spectroscopic techniques.
We synthesize noble metal nanoparticles and nanoclusters and apply them in drug delivery following biological compatibility. The metal nanoclusters show fluorescence signals as opposed to the nanoparticles that makes them usable as bio-markers. Guest-host chemistry can be applied to develop bio-remedies for various physiological malfunctions.
Photoinduced electron transfer is a smart concept to learn as this encompasses various applications including energy harvesting devices. We use carbon based nanomaterials, including nanoparticles, nanotubes and nanoplatelets to look into interactions with various energy donating/accepting substances in view of understanding the underlying dynamics.
New organic compounds are synthesized in this venture through structural engineering and crystals are produced intuitively so that the materials can be used various applications including light guides, OLEDs, room temperature phosphorescent substances, etc.
These microscopy based techniques are used in our laboratory to justify the positioning of various guests in bio-compatible hosts, such as, lipid vesicles. Entrapment of the fluorescent species withing bilayers alters the inherent photophysics of the guests that are significant to understand before applications to drug delivery.